MCAS New River is the principal USMC helicopter operating location on the East Coast, and supports aircrew training in the H-53 helicopter.The Air Station is the only Marine Corps base with the new MV-22 Osprey. It has the ability to fly like a plane, and take off and land like a helicopter. The MV-22 is slowly replacing the CH-46E medium lift helicopter. Currently there are six operational Osprey squadrons, VMM-261, VMM-263, VMM-162, VMM-365, VMM-264, and VMM-266.

Situated along the New River next door to Camp Lejeune is the city of Jacksonville in Onslow County. Settled in the early 1700s, Onslow County has rich and diverse history stemming from the agricultural, timber, and fishing pursuits begun by the English and Scottish natives who settled here. Since 1941 Onslow County has been home to Camp Lejeune and Air Station New River Marines and Sailors, many of whom relocate here following retirement or discharge.